ceesdekker.net - An Overview
ceesdekker.net - An Overview
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It absolutely was only inside the nineteen nineties however, when nanotechnology experienced Superior to the level wherever single molecules could be manipulated, that the 1st experimental gadgets started to look.
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
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Our investigation ranges through the biophysics of DNA to artificial cells and over and above. Remember to have a look beneath in the spectrum of our present tasks.
All parameters have been the exact same for every panel During this video, except for the initial placement in the 6hb rod (demonstrated in blue) to the nanopore. Simulations that terminated early as a consequence of translocation with the rod throughout the pore are marked by a grey qualifications.
2011, first in vitro measurements of transportation throughout an individual biomimetic nuclear pore intricate; advancement of multiplexed magnetic tweezers for kilo-molecule experiments; and settled the mechanism of homology recognition in DNA homologous recombination
‘You should not just think about the concerns of tomorrow, but also think about the concerns from the day after tomorrow’
‘The fantastically refined way through which factors in nature function hardly ever ceases to amaze cees dekker me. If we clear up the puzzle of how daily life came into being, I be expecting that my amazement with the complexity of creation will have greater and with it my awe to the greatness from the Creator.’
Tests pseudotopological and nontopological models for SMC-driven DNA loop extrusion from roadblock-traversal experiments
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2008, initial observation of protein-coated DNA translocation via nanopores; resolved the origin of the electrophoretic force on DNA in nanopores; found out an important velocity raise of microtubules in electrical fields; uncovered an anomalous electro-hydrodynamic orientation of microtubules; and settled the origin of noise in carbon nanotubes in liquid
2004, discovery of latest physics in translocation of DNA through nanopores; initially experimental examine of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization with the mechanical Qualities of double-stranded RNA; and to start with solitary-molecule analyze of DNA translocation by a restriction-modification enzyme.